The biggest college football matchups for Week 5 are predicted, and Hurricane Ian’s effects might change how many games are played this week due to the rainy and muddy weather. Keep an eye on Saturday night’s top-10 battle between Clemson and NC State, as the storm is predicted to pass over South Carolina during the game.

Given the Tigers’ loss to the Wolfpack last year and the anticipated close game this weekend at Memorial Stadium, we’re putting the Tigers on upset alert.
Second-ranked Alabama travels to Arkansas and will try and capture its 15th consecutive win in the SEC West series. Another crucial SEC matchup between the unbeaten teams Kentucky and Ole Miss will take place in Oxford in Week 5.
Week 5 College Football Predictions 2022
In terms of the playoff and conference championship races, Week 4 was rife with changes and potential changes. Overall, I still over 75% for the week, and with a record of 50-16 for the year, I am now 236-67. My Week 5 predictions will now follow.
South Carolina State 7 @ South Carolina 45
Utah State 14 @ BYU 41
Tulane 23 @ Houston 21
UTSA 32 @ Middle Tennessee 21
San Diego State 13 @ Boise State 16
Washington 31 @ UCLA 25
New Mexico 14 @ UNLV 28
Georgia State 10 @ Army 21
Illinois 21 @ Wisconsin 27
Louisville 37 @ Boston College 28
Michigan 21 @ Iowa 9
Navy 14 @ Air Force 24
Oklahoma 37 @ TCU 33
Purdue 18 @ Minnesota 32
Temple 10 @ Memphis 35
Texas Tech 24 @ Kansas State 31
Kentucky 21 @ Ole Miss 27
Texas State 13 @ James Madison 48
Northern Illinois 17 @ Ball State 20
Oregon State 27 @ Utah 28
UMass 12 @ Eastern Michigan 31
East Carolina 27 @ USF 7
Alabama 34 @ Arkansas 21
Bowling Green 28 @ Akron 16
The Citadel 3 @ Appalachian State 41
Central Michigan 23 @ Toledo 27
Fresno State 37 @ UConn 6
Gardner-Webb 14 @ Marshall 56
Iowa State 28 @ Kansas 38
Miami Ohio 23 @ Buffalo 21
Michigan State 27 @ Maryland 24
Northwestern 17 @ Penn State 47
Ohio 20 @ Kent State 28
Oklahoma State 24 @ Baylor 27
Rutgers 13 @ Ohio State 62
Virginia Tech 31 @ North Carolina 45
Wake Forest 38 @ Florida State 48
FAU 34 @ North Texas 30
Georgia Southern 21 @ Coastal Carolina 26
Texas A&M 24 @ Mississippi State 20
South Alabama 31 @ ULL 29
Wagner 7 @ Syracuse 45
Cal 18 @ Washington State 27
Liberty 21 @ Old Dominion 22
New Hampshire 13 @ Western Michigan 27
UTEP 21 @ Charlotte 32
Cincinnati 27 @ Tulsa 11
ULM 24 @ Arkansas State 35
LSU 37 @ Auburn 12
Troy 17 @ Western Kentucky 27
Indiana 31 @ Nebraska 28
NC State 34 @ Clemson 31
San Jose State 23 @ Wyoming 16
UAB 35 @ Rice 25
Georgia 35 @ Missouri 0
Virginia 26 @ Duke 24
West Virginia 17 @ Texas 30
FIU 14 @ New Mexico State 17
Georgia Tech 13 @ Pittsburgh 44
Colorado 10 @ Arizona 34
Arizona State 23 @ USC 55
Stanford 14 @ Oregon 37
Eastern Washington 24 @ Florida 48
SMU 31 @ UCF 41
Why is this spread just 10.5 points since Lowa hasn’t scored a touchdown in its previous 10 quarters versus Michigan and lost by 39 the last time these two teams played? Given that Michigan hasn’t triumphed at Kinnick Stadium in more than a decade, oddsmakers are giving the Hawkeyes much too much credit.